ʻO ka Cytomegalovirus kanaka (HCMV) Nucleic Acid

ʻO ka cytomegalovirus kanaka (HCMV) he lālā me ka genome nui loa i ka ʻohana maʻi herpes a hiki ke hoʻopili i nā protein ma mua o 200.Ua kaupalena ʻia ka HCMV i nā kānaka, a ʻaʻohe kumu hoʻohālike holoholona o kona maʻi.He lohi a lōʻihi ka hoʻololi hou ʻana o ka HCMV e hana i kahi kino hoʻokomo intranuclear, a hoʻomaka i ka hana ʻana o nā kino perinuclear a me nā cytoplasmic inclusion a me ka pehu ʻana o ke kelepona (nā mea nunui), no laila ka inoa.Wahi a ka heterogeneity o kona genome a me ka phenotype, hiki ke hoʻokaʻawale ʻia ka HCMV i nā ʻano ʻano like ʻole, aia kekahi mau ʻano antigenic, akā naʻe, ʻaʻole ia he kumu koʻikoʻi.

ʻO ka maʻi HCMV he maʻi ʻōnaehana, e pili ana i ka maʻi maʻi i nā ʻano he nui, he paʻakikī a ʻano hōʻailona like ʻole, ka hapa nui o ka leo, a hiki ke hoʻoulu i kekahi mau maʻi e hoʻomohala i nā maʻi he nui e like me ka retinitis, hepatitis, pneumonia, encephalitis, colitis, monocytosis, a me thrombocytopenic. purpura.He mea maʻamau ka maʻi HCMV a ʻike ʻia e laha a puni ka honua.He nui loa ia i ka heluna kanaka, me ka nui o ka nui o 45-50% a ʻoi aku ma mua o 90% ma nā ʻāina kūkulu a me nā ʻāina ulu, kēlā me kēia.Hiki i ka HCMV ke moe i loko o ke kino no ka manawa lōʻihi.Ke hoʻonāwaliwali ʻia ka pale ʻana o ke kino, e hoʻāla ʻia ka maʻi maʻi i mea e hoʻoulu ai i nā maʻi, ʻoi aku ka nui o nā maʻi maʻi i nā maʻi leukemia a me nā maʻi transplanted, a hiki ke hoʻoulu i ka necrosis o ke kino a hoʻoweliweli i ke ola o nā maʻi i nā maʻi koʻikoʻi.Ma waho aʻe o ka hānau ʻana, ka hāʻule ʻole a me ka hānau mua ʻana ma o ka maʻi intrauterine, hiki i ka cytomegalovirus ke hoʻoulu i nā hemahema congenital, no laila hiki i ka maʻi HCMV ke hoʻopilikia i ka mālama prenatal a me ka postnatal a me ka maikaʻi o ka heluna kanaka.