Mycobacterium Tuberculosis Nucleic Acid a me Rifampicin Resistance

ʻO ka Mycobacterium tuberculosis ， ʻoiai ʻo Tubercle bacillus, TB, ʻo ia ka maʻi maʻi pathogenic e kumu ai ka maʻi maʻi.I kēia manawa, ʻo nā lāʻau anti-tuberculosis laina mua i hoʻohana pinepine ʻia me isoniazid, rifampicin a me hexambutol, a me nā mea ʻē aʻe. Eia nō naʻe, ma muli o ka hoʻohana hewa ʻana i nā lāʻau anti-tuberculosis a me nā ʻano o ke ʻano o ka pā hale o ka mycobacterium tuberculosis, ua hoʻomohala ka mycobacterium tuberculosis i ka lāʻau kūʻē i nā lāʻau anti-tuberculosis, e lawe mai ana i nā pilikia koʻikoʻi i ka pale ʻana a me ka mālama ʻana i ka maʻi maʻi.

Ua hoʻohana nui ʻia ka Rifampicin i ka mālama ʻana i nā maʻi maʻi maʻi maʻi mai ka hopena o 1970s, a he hopena koʻikoʻi.ʻO ia ke koho mua e hoʻopōkole i ka chemotherapy o nā maʻi maʻi maʻi maʻi pulmonary.ʻO ke kūʻē ʻana o Rifampicin ma muli o ka hoʻololi ʻana o ka gene rpoB.ʻOiai ke puka mau nei nā lāʻau anti-tuberculosis hou, a ke hoʻomau nei ka maikaʻi o ka lāʻau lapaʻau o ka poʻe maʻi maʻi maʻi pulmonary tuberculosis, aia nō ka nele o nā lāʻau anti-tuberculosis, a ʻoi aku ka kiʻekiʻe o ke ʻano o ka hoʻohana ʻana i ka lāʻau lapaʻau ʻole.Akaka, ka Mycobacterium tuberculosis i loko o nā mea maʻi me ka pulmonary tuberculosis hiki ole loa pepehi i loko o ka manawa, ka mea hope alakai i ka likeʻole degere o ka lāʻau kū'ē i loko o ke kino o ka mea maʻi, hoʻolōʻihi i ka papa o ka maʻi, a hoʻonui i ka pilikia o ka make o ka mea maʻi.