Progesterone (P)

He progestogen koʻikoʻi ka Progesterone, no nā hormones steroid, me ke kaumaha molekala pili o 314.5.Hana ʻia ia e ka corpus luteum o ka ovary a me ka placenta i ka wā hāpai.ʻO ia ka precursor o testosterone, estrogen a me adrenal cortex hormones.ʻO ka pae progesterone i hana ʻia i ka wā follicular o nā kāne a me nā wahine maʻamau he haʻahaʻa loa, ma hope o ka huna ʻana i loko o ke koko, ua paʻa nui ia i ka albumin a me ka sex hormone hoʻopaʻa i ka protein a kaʻahele i loko o ke kino.

ʻO ka hana nui o ka progesterone ʻo ia ka hoʻomākaukau ʻana i ka ʻōpū no ka hoʻokomo ʻana i nā hua momona a mālama i ka hāpai ʻana.I ka manawa follicular o ka menstrual cycle, haʻahaʻa ka pae progesterone.Ma hope o ka ovulation, piʻi wikiwiki ka progesterone i hana ʻia e ka corpus luteum, a hiki i ka ʻoi loa o ka 10ng/mL-20ng/mL i nā lā 5-7 ma hope o ka ovulation.Inā ʻaʻole i hāpai ʻia, atrophies ke kino luteum i nā lā ʻehā i hala o ka pōʻai menstrual a e emi ana ka neʻe o ka progesterone i ka pae follicular.Inā hāpai ʻia, ʻaʻole e mae ka corpus luteum a hoʻomau i ka huna ʻana i ka progesterone, e mālama ana ia i nā pae e like me ka manawa luteal medium a hoʻomau a hiki i ke ono o ka pule o ka hāpai ʻana.I ka wā o ka hāpai ʻana, lilo ka placenta i kumu nui o ka progesterone, a piʻi ka manaʻo mai 10ng/mL-50ng/mL i nā mahina 3 mua o ka hāpai ʻana i 50ng/mL-280ng/mL i nā mahina 7-9.Ua hōʻike nā haʻawina maʻi i ka hana o ka progesterone i ka hāpai ʻana i ka ovulation a me ka mālama ʻana i ka hana maʻamau o ka corpus luteum i nā wahine hāpai ʻole.Inā ʻaʻole lawa ka progesterone i hana ʻia e ka corpus luteum, hiki ke hōʻike i ka lawa ʻole o ka hana o ke kino, a ʻo ka lawa ʻole o ka corpus luteum e pili ana i ka infertility a me ka hāʻule mua ʻana.