KRAS 8 Hoololi

ʻO ka wehewehe pōkole:

Kuhi ʻia kēia pahu no ka ʻike in vitro qualitative o 8 mau hoʻololi i nā codons 12 a me 13 o K-ras gene i loko o ka DNA i unuhi ʻia mai nā ʻāpana pathological i hoʻopili ʻia e ke kanaka.


Huahana Huahana

Huahana Huahana

Inoa mea kūʻai

HWTS-TM014-KRAS 8 Mea ʻIke Hoʻololi (Fluorescence PCR)

HWTS-TM011-KRAS 8 Mutations Detection Kit (Fluorescence PCR) i maloʻo maloʻo.

Palapala

CE

Epidemiology

Ua ʻike ʻia nā hoʻololi ʻana o ka helu ma ka KRAS gene i loko o kekahi mau ʻano maʻi maʻi kanaka, ma kahi o 17% ~ 25% ka nui o ka mutation i ka ʻōpū, 15% ~ 30% ka nui o ka hoʻololi ʻana i nā maʻi maʻi maʻi akemāmā, 20% ~ 50% ka nui o ka mutation ma ka maʻi maʻi colorectal nā maʻi.No ka mea, aia ka pūmua P21 i hoʻopaʻa ʻia e ka K-ras gene i lalo o ke ala hōʻailona EGFR, ma hope o ka hoʻololi ʻana o ke ʻano K-ras, e hoʻāla mau ʻia ke ala hōʻailona o lalo a ʻaʻole pili ʻia e nā lāʻau lapaʻau i hoʻopaʻa ʻia ma luna o EGFR, e hopena i ka hoʻomau. ka hoʻomāinoino ʻana o nā cell.ʻO ka hoʻololi ʻana i ka moʻo K-ras e hāʻawi maʻamau i ke kūʻē ʻana i nā mea hoʻopaneʻe tyrosine kinase EGFR i nā poʻe maʻi maʻi ʻāʻī a me ke kūʻē ʻana i nā lāʻau anti-EGFR antibody i nā maʻi maʻi maʻi colorectal.I ka makahiki 2008, ua hoʻopuka ka National Comprehensive Cancer Network (NCCN) i kahi alakaʻi hoʻomaʻamaʻa lapaʻau no ka maʻi maʻi colorectal, i kuhikuhi ʻia ʻo nā pūnaewele mutation e hoʻāla ʻia ai ʻo K-ras ka nui i nā codons 12 a me 13 o exon 2, a ua ʻōlelo ʻia e Hiki ke ho'āʻo ʻia nā poʻe maʻi āpau me ka maʻi maʻi maʻi metastatic colorectal kiʻekiʻe no ka mutation K-ras ma mua o ka mālama ʻana.No laila, he mea koʻikoʻi ka ʻike wikiwiki a me ka pololei o ka hoʻololi ʻana o ka gene K-ras i ke alakaʻi ʻana i ka lāʻau lapaʻau.Hoʻohana kēia kit i ka DNA ma ke ʻano he laʻana ʻike e hāʻawi i ka loiloi qualitative o ke kūlana mutation, hiki ke kōkua i nā kauka i ka nānā ʻana i ka maʻi maʻi colorectal, ka maʻi maʻi ʻāʻī a me nā maʻi maʻi ʻē aʻe e pōmaikaʻi ana i nā lāʻau lapaʻau.ʻO nā hopena hoʻāʻo o ka kit no ka hōʻike lapaʻau wale nō a ʻaʻole pono e hoʻohana ʻia ma ke kumu hoʻokahi no ka mālama ʻana i nā maʻi.Pono nā kauka lapaʻau e hoʻoholo i nā hopena hōʻike ma muli o nā kumu e like me ke kūlana o ka mea maʻi, nā hōʻailona lāʻau, ka pane ʻana a me nā hōʻailona hoʻokolohua ʻē aʻe.

Nā ʻāpana ʻenehana

Waihona Ka wai: ≤-18 ℃ I ka pōʻeleʻele;Lyophilized: ≤30 ℃ I ka pōʻeleʻele
Kau-ola Ka wai: 9 mahina;Lyophilized: 12 mahina
ʻAno Hoʻohālike ʻO ka ʻiʻo pathological i hoʻokomo ʻia i ka paraffin a i ʻole ka ʻāpana i loaʻa nā cell tumorous
CV ≤5.0%
LoD Hiki iā K-ras Reaction Buffer A a me K-ras Reaction Buffer B ke ʻike paʻa i ka 1% ka nui o ka hoʻololi ʻana ma lalo o 3ng/μL ʻano ʻano hihiu.
Nā mea hana pili Hoʻohana ʻia Biosystems 7500 Pūnaehana PCR manawa maoli

Hoʻohana ʻia Biosystems 7300 Pūnaehana PCR manawa maoli

QuantStudio®5 Pūnaehana PCR Manawa maoli

LightCycler® 480 Pūnaehana PCR manawa maoli

BioRad CFX96 Pūnaehana PCR Manawa maoli

Holo Hana

Manaʻo ʻia e hoʻohana i ka QIAGEN's QIAamp DNA FFPE Tissue Kit (56404) a me Paraffin-embedded Tissue DNA Rapid Extraction Kit (DP330) i hana ʻia e Tiangen Biotech(Beijing) Co., Ltd.


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