MTHFR Gene Polymorphic Nucleic Acid

ʻO ka wehewehe pōkole:

Hoʻohana ʻia kēia pahu no ka ʻike ʻana i nā pae hoʻololi ʻelua o ka gene MTHFR.Hoʻohana ka pahu i ke koko holoʻokoʻa o ke kanaka ma ke ʻano he laʻana hoʻāʻo e hāʻawi i kahi loiloi qualitative o ke kūlana mutation.Hiki iā ia ke kōkua i nā kauka e hoʻolālā i nā hoʻolālā lapaʻau kūpono no nā ʻano like ʻole o kēlā me kēia kanaka mai ka pae molekala, i mea e hōʻoia ai i ke olakino o nā maʻi i ka nui loa.


Huahana Huahana

Huahana Huahana

Inoa mea kūʻai

HWTS-GE004-MTHFR Gene Polymorphic Nucleic Acid Detection Kit (ARMS-PCR)

Epidemiology

ʻO ka ʻakika Folic kahi huaʻai hiki ke hoʻoheheʻe ʻia i ka wai he cofactor pono i nā ala metabolic o ke kino.I nā makahiki i hala iho nei, ua hōʻoia ka nui o nā haʻawina, ʻo ka mutation o ka folate metabolizing enzyme gene MTHFR e alakaʻi i ka hemahema o ka waikawa folic i loko o ke kino, a ʻo ka pōʻino maʻamau o ka nele o ka folic acid i nā pākeke ke kumu i ka anemia megaloblastic, vascular. endothelial pōʻino, etc. ʻAʻole hiki i ka nele o ka waikawa folic i nā wahine hāpai ke hoʻokō i nā pono o lākou iho a me ka ʻōpū, hiki ke hoʻopilikia i ka neural tube, anencephaly, hānau keiki, a me ka hāʻule ʻole.Hoʻopili ʻia nā pae serum folate e 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms.ʻO nā hoʻololi 677C>T a me 1298A>C i loko o ka MTHFR gene e hoʻohuli i ka hoʻololi ʻana o ka alanine i valine a me ka glutamic acid, kēlā me kēia, ka hopena o ka hana MTHFR a hoʻemi i ka hoʻohana ʻana i ka waikawa folic.

Kanal

FAM MTHFR C677T
ROX MTHFR A1298C
VIC(HEX) Ka hooponopono kuloko

Nā ʻāpana ʻenehana

Waihona

≤-18 ℃

Kau-ola

12 mahina

ʻAno Hoʻohālike

ʻO ke koko anticoagulated EDTA i hōʻiliʻili hou ʻia

CV

≤5.0%

Ct

≤38

LoD

1.0ng/μL

Nā mea hana pili:

Hoʻohana ʻia Biosystems 7500 Pūnaehana PCR manawa maoli

Hoʻohana ʻia ʻo Biosystems 7500 Fast Real-Time PCR Systems

SLAN ®-96P Pūnaehana PCR Manawa maoli

QuantStudio™ 5 Pūnaehana PCR Manawa maoli

LightCycler®480 Pūnaehana PCR manawa maoli

LineGene 9600 Plus Pūnaehana ʻike PCR manawa maoli

MA-6000 ʻOiaʻiʻo ka nui o ka wela wela

BioRad CFX96 Pūnaehana PCR Manawa maoli

BioRad CFX Opus 96 Pūnaehana PCR Manawa maoli

Holo Hana

Koho 1

Manaʻo ʻia nā reagents unuhi: Macro & Micro-Test Genomic DNA Kit (HWTS-3014-32, HWTS-3014-48, HWTS-3014-96) a me Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006C, HWTS-3006B) .

Koho 2

Manaʻo ʻia nā mea hoʻihoʻi hou: Blood Genomic DNA Extraction Kit(YDP348, JCXB20210062) na Tiangen Biotech(Beijing) Co., Ltd.Koko Genome Extraction Kit(A1120) na Promega.


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